SMRTR Science & EngineeringJun 3, 2026Reddit

Injectable hydrogel relieves osteoarthritis pain and repairs cartilage in preclinical tests

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Yale researchers discovered that lacosamide, an existing epilepsy drug, can both relieve osteoarthritis pain and repair cartilage by blocking an overactive protein called Nav1.7. Delivered via an injectable smart gel that slowly releases the drug over weeks, a single monthly injection outperformed daily oral medication in preclinical trials.

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