SMRTR Science & EngineeringJan 23, 2025Science Daily

Boosting this molecule could help retain muscle while losing fat

SMRTR summary

The Salk Institute's study identified BCL6 protein as vital for maintaining muscle mass. Mice without BCL6 had 40% less muscle mass and weaker muscles, while increasing BCL6 reversed these effects. This discovery may lead to treatments for muscle loss in people using GLP-1 weight loss drugs, older adults, and certain patients. Combining GLP-1 medications with BCL6-boosting drugs might prevent unwanted muscle loss during weight loss treatment.

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