SMRTR Science & EngineeringMar 8, 2026Scientific American

Why ‘quantum proteins’ could be the next big thing in biology

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Researchers have discovered that common fluorescent proteins used in biology labs can be transformed into quantum sensors by harnessing their triplet electron states, previously considered an unwanted side effect. Teams at the University of Chicago and other institutions demonstrated that these "quantum proteins" can detect magnetic fields with extraordinary sensitivity, potentially enabling detection of firing neurons, cellular stress markers, and early cancer signs. Unlike bulky diamond-based quantum sensors, these proteins can be genetically programmed to appear precisely where needed inside living cells. The breakthrough could revolutionize medical imaging by combining MRI-like deep tissue penetration with protein-specific fluorescent labeling, though researchers are still working to improve the proteins' fragility and sensitivity.

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