SMRTR Science & EngineeringAug 20, 2025The Economist

The discovery of a gene for chronic pain could herald new treatments

SMRTR summary

Researchers have identified a gene variant, SCN11A, associated with chronic pain, potentially leading to better treatments for millions of sufferers. This gene causes nerve cells to fire more easily, increasing pain sensitivity. The discovery explains why some people develop chronic pain while others with similar injuries don't. This breakthrough could enable the development of targeted drugs, potentially transforming treatment for the one in five adults struggling with chronic pain.

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