Supercomputer decodes protein ‘language,’ offering new clues to fight cancer

Scientists at the University of Glasgow used the Tursa supercomputer to create PLM-Interact, an AI model that deciphers protein communication. The model predicts protein interactions with 16% to 28% greater accuracy than existing tools like Google DeepMind's AlphaFold3, successfully identifying five key protein interactions compared to just one by other models. PLM-Interact can forecast which mutations disrupt protein communication, offering insights into cancer development and viral infections. This breakthrough could accelerate development of new treatments and vaccines.