SMRTR Science & EngineeringMay 10, 2026Science Daily

Scientists found the “holy grail” gene that could one day help humans regrow limbs

SMRTR summary

Scientists studying axolotls, zebrafish, and mice have identified a set of genes called SP genes that drive limb regeneration across all three species. Using CRISPR, researchers confirmed that removing SP8 prevented proper bone regrowth in salamanders. A gene therapy delivering a related molecule partially restored regeneration in mice, suggesting that similar treatments could one day help the over one million people who lose limbs annually.

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