SMRTR Science & EngineeringJan 5, 2026Science Daily

Scientists find a safer way to make cells burn more calories

SMRTR summary

Scientists have developed experimental compounds called "mild mitochondrial uncouplers" that safely increase cellular energy use and calorie burning by disrupting how mitochondria convert food into usable power. Unlike dangerous weight-loss chemicals from the past that caused fatal overheating, these new molecules carefully control the uncoupling process to avoid toxic effects while boosting metabolism. Research from University of Technology Sydney suggests these compounds could offer a safer path to treating obesity compared to current injection-based medications with unwanted side effects.

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