SMRTR Science & EngineeringFeb 24, 2025Interesting Engineering

Scientists achieve 3D molecular mapping with breakthrough hybrid microscope

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Scientists have developed a hybrid microscope that captures both 3D orientation and position of molecular structures like proteins inside cells. The instrument combines polarized fluorescence with a dual-view light sheet microscope, allowing researchers to record changes in 3D protein orientation and overcome limitations of traditional microscopy when imaging tilted structures.

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