SMRTR Science & EngineeringJul 15, 2025Science News

Protein signatures may one day tell brain diseases apart before symptoms

SMRTR summary

A large-scale study of proteins in blood and cerebrospinal fluid has revealed biochemical fingerprints of neurodegenerative disorders like Alzheimer's and Parkinson's. The research, involving samples from 18,645 people, could lead to improved blood tests for diagnosing brain diseases and identifying early warning signs. Key findings include a shared blood signature in APOE4 gene carriers and distinct protein patterns for different neurodegenerative diseases.

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