SMRTR Science & EngineeringJan 21, 2025Scientific American

Mysterious Blobs Found in Cells Are Rewriting How Life Works

SMRTR summary

Biomolecular condensates, microscopic liquid-like droplets of proteins and RNA within cells, have transformed our view of cellular organization. These membrane-less structures perform essential functions across all life forms, including protecting cells from stress, repairing DNA damage, and regulating gene expression. Condensates are vital for coordinating cellular processes and may be implicated in diseases like cancer and neurodegeneration. Researchers are now investigating condensates as potential therapeutic targets, with some drugs already in clinical trials.

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