SMRTR Science & EngineeringSep 28, 2025Science News

In a first, Huntington’s disease is slowed by an experimental treatment

SMRTR summary

An experimental gene therapy delivered directly to the brain has slowed Huntington's disease progression by up to 75 percent over three years in a small clinical trial of 17 patients. The treatment uses virus-delivered microRNA to reprogram brain cells to stop producing the toxic huntingtin protein that causes the fatal disease.

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