SMRTR Science & EngineeringOct 7, 2025Scientific American

First-of-Its-Kind Kidney Transplant Could Lead to More Cross-Blood Type Donations

SMRTR summary

Scientists successfully converted a type-A donor kidney to universal type-O by using enzymes to remove specific antigens, then transplanted it into a brain-dead patient where it functioned for six days. This breakthrough could eliminate blood type matching requirements for organ transplants, potentially expanding the donor pool and reducing wait times for patients needing life-saving organs.

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