Clumps of mouse brain cells can learn to play a virtual game

Mouse brain organoids the size of peppercorns successfully learned to balance a virtual pole on a moving cart through electrical feedback training, demonstrating short-term learning abilities. The organoids achieved the 20-second balance threshold nearly half the time with coaching, compared to less than 5 percent without proper training. However, they lost their skills after 45-minute breaks and required retraining, suggesting they lack the complex neural pathways needed for long-term memory retention.