SMRTR Science & EngineeringJan 2, 2025Science Daily

CAR-T cells hold memories of past encounters

SMRTR summary

University of Colorado researchers discovered that CAR-T cells, used to fight cancer, retain memories of past encounters with antigens. This finding could lead to more precise engineering of CAR-T cells for improved cancer treatment. The study revealed that "memory" cells kill cancer quickly but exhaust sooner, while "naïve" cells show better disease-fighting capabilities when enhanced with genes like RUNX2.

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