SMRTR Science & EngineeringDec 16, 2025Live Science

Brain scans reveal 'dial' that helps keep us from getting lost

SMRTR summary

Scientists discovered that the human brain contains a gradient system in the hippocampus that acts like a "dial" to distinguish between familiar and new environments, with one end responding to known areas and the other to unfamiliar territory. This finding could explain why navigation problems are early dementia symptoms, since these brain regions are among the first affected by Alzheimer's disease.

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