SMRTR Science & EngineeringFeb 20, 2025Science Daily

Biologists discover a new type of control over RNA splicing

SMRTR summary

MIT biologists discovered a new layer of RNA splicing regulation involving LUC7 proteins, which affects up to 50% of human genes. This mechanism, found in plants and animals but not fungi, adds complexity to gene expression control by targeting specific intron types, potentially impacting diseases like acute myeloid leukemia and offering new therapeutic opportunities.

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