SMRTR Science & EngineeringFeb 22, 2026Scientific American

‘An AlphaFold 4’—scientists marvel at DeepMind drug spin-off’s exclusive new AI

SMRTR summary

Isomorphic Labs, Google DeepMind's drug discovery spin-off, unveiled IsoDDE, an AI system that dramatically outperforms existing tools at predicting how proteins interact with potential drugs and antibodies. Unlike previous AlphaFold releases, the company is keeping this breakthrough technology proprietary, leaving academic researchers unable to replicate the advances.

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